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Table 1 Significant recombination events detected among NAT genes using six different methods

From: Rapid birth-and-death evolution of the xenobiotic metabolizing NAT gene family in vertebrates with evidence of adaptive selection

Species Genes 5' breakpointa 3' breakpointa Length (bp)a P-value rangeb Methodsb
Rattus norvegicus NAT1 : NAT2 382/385/401 609/611 209/225/230 9.06 E-3–1.00 E-6 GeneConv, RDP, MaxChi, Chimaera, Bootscan, SiScan
Oryzias latipes NAT1 : NAT2 1 260/262 260/262 8.87 E-3–6.39 E-6 Geneconv, RDP, MaxChi, Chimaera, Bootscan
Echinops telfairi NAT1 : NAT2 43 642 600 1.00 E-4 Geneconv
Myotis lucifugus NAT1 : NAT2 600/615 742/749 128/150 6.06 E-4–1.39 E-4 MaxChi, Chimaera,
Mus musculus NAT1 : NAT2 382 518 137 2.00 E-4 Geneconv
Mesocricetus auratus NAT1 : NAT2 1 155/163/167 155/163/167 9.32 E-3–2.93 E-4 RDP, Chimaera, Bootscan, SiScan
Myotis lucifugus NAT1 : NAT2 1 204 204 3.00 E-4 Geneconv
Danio rerio NAT2 : NAT3 88 507 420 7.90 E-3 Geneconv
  1. a Breakpoint positions refer to the nt positions in the full alignment of the vertebrate NAT sequences. They may slightly vary depending on the method used to detect recombinant sequences, leading to different gene conversion tract lengths.
  2. b In cases where multiple methods detected the same or a similar conversion event, we reported the P-value range, i.e. the worst and the best P-value; the method yielding the best P-value is shown in bold. Otherwise, only the P-value of the single algorithm detecting a conversion event is presented.