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Table 2 Likelihood ratio tests using various models to determine the selective pressures on the cetacean Hr gene

From: Characterization of hairless (Hr) and FGF5genes provides insights into the molecular basis of hair loss in cetaceans

Models

ω(d N /d S )

lnLa

npb

Models compared

2Δ(lnL)c

P-values

Dataset I: 17 sequences (16 terrestrial mammals plus the ancestral cetacean sequence)

      

A. All branches with the same ω

ω = 0.27908

−24914.624502

34

   

B. Branch a (ancestral to cetacean) with ω2, other branches with ω1

ω1 = 0.27502, ω2 = 0.40432

−24912.059374

35

A vs B

5.130256

0.024

C. Branch a with ω2 = 1, other branches with ω1

ω1 = 0.27427, ω2 = 1

−24925.508371

34

B vs C

26.89799

2.14E-07

Dataset II: 19 sequences (16 terrestrial mammals plus two baleen whales and the ancestral sequence of toothed whales)

      

D. All branches with the same ω

ω = 0.28065

−25530.203259

38

   

E. Branch b (ancestral to toothed whale) with ω2, other branches with ω1

ω1 = 0.27911, ω2 = 0.48639

−25528.780477

39

D vs E

2.845564

0.092

F. Branch b with ω2 = 1, other branches with ω1

ω1 = 0.27890, ω2 = 1

−25530.928574

38

E vs F

4.296194

0.038

Dataset III: 22 sequences (16 terrestrial mammals plus five toothed whales and the ancestral sequence of baleen whales)

      

G. All branches with the same ω

ω = 0.28417

−26239.723434

44

   

H. Branch c (ancestral to baleen whale) with ω2, other branches with ω1

ω1 = 0.28182, ω2 = 0.62531

−26236.569206

45

H vs G

6.308456

0.012

I. Branch c with ω2 = 1, other branches with ω1

ω1 = 0.28170, ω2 = 1

−26237.557075

44

H vs I

1.975738

0.160

  1. Note: a, ln L is the log-likelihood score; b, number of parameters; c, twice the difference in ln L between the two models compared.