TY - JOUR AU - Lopes-Marques, Mónica AU - Cunha, Isabel AU - Reis-Henriques, Maria Armanda AU - Santos, Miguel M. AU - Castro, L. Filipe C. PY - 2013 DA - 2013/12/12 TI - Diversity and history of the long-chain acyl-CoA synthetase (Acsl) gene family in vertebrates JO - BMC Evolutionary Biology SP - 271 VL - 13 IS - 1 AB - Fatty acids, a considerable fraction of lipid molecules, participate in fundamental physiological processes. They undergo activation into their corresponding CoA esters for oxidation or esterification into complex lipids (e.g. triglycerides, phospholipids and cholesterol esters), a process that is carried out by acyl-CoA synthases (ACS). Here we analyze the evolution of the gene family encoding for the long-chain acyl-CoA synthetases (Acsl) in vertebrates. SN - 1471-2148 UR - https://doi.org/10.1186/1471-2148-13-271 DO - 10.1186/1471-2148-13-271 ID - Lopes-Marques2013 ER -