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Table 3 Measures of ongoing selective pressures in human populations for a subset of telomere associated genes

From: Molecular adaptation of telomere associated genes in mammals

Gene name and significance level iHS A C Y Total SNPs
ATM @5% > +2 3 5 0 158
< -2 0 3 18
BRCA1 @5% > +2 0 1 0 108
< -2 0 0 1
WRN @10% > +2 0 2 2 306
< -2 0 1 10
RBL1 @10% > +2 0 0 0 88
< -2 1 0 0
ANKHD1 @5% > +2 0 0 0 49
< -2 0 1 1
  1. Each gene identified as diverging within the ancestral human population at p-adj (0.05) and p-adj (0.10) significance levels under the CladeC model are listed with the number of SNPs with iHS > 2 and the number of SNPs with an iHS < -2 for the East Asian (A), northern and Western European (C), and African Yoruba (Y) populations. The total number of SNPs known for each gene is given in the final column.
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BMC Ecology and Evolution

ISSN: 2730-7182

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