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Figure 6 | BMC Evolutionary Biology

Figure 6

From: Not so pseudo: the evolutionary history of protein phosphatase 1 regulatory subunit 2 and related pseudogenes

Figure 6

Conserved linkage of PPP1R2P9. PPP1R2P9 location in terms of chromosome and flanking genes is presented concerning each species where was found, showing the conserved linkage. Divergence time is shown on the left. The nucleotide number flanking the pseudogenes is related to the parental PPP1R2 message. Grey boxes refer to the LINE1 elements. Black boxes refer to SINEs B2 repeats that are rodent-specific and to the tRNAs present in the horse (Equus caballus) and in the giant panda sequences. Checkered box refers to long terminal repeat (LTR) in the giant panda sequence, which is an endogenous retroviral-related element (ERVL). Number above the boxes states the location where the repeat interrupted the sequence. Numbers inside the boxes indicate if there is more than one in line. Grey box delimited with a black line in marmoset PPP1R2P9-like refer to a parental PPP1R2 insertion. Number on the top refers where the insertion took place in the pseudogene, while numbers at the bottom show which region of the parental PPP1R2 was inserted. In mouse an unknown sequence according to the current genome assembly was inserted in PPP1R2P9-like and is shown with a number referring to its location. Also, a deletion is shown in mouse (1067 to 1373) and in rat (1065 to 1373) PPP1R2P9-like pseudogenes. The distances in dashed lines of the other retroposed forms in marmoset, mouse, rat and pig are also indicated. CASK: calcium/calmodulin-dependent serine protein kinase; MAOA: monoamine oxidase A.

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