Figure 2From: Contrasted evolutionary histories of two Toll-like receptors (Tlr4 and Tlr7) in wild rodents (MURINAE)Distribution of sites under selection identified by SLAC and MEME. Intensity of selection acting on Tlr4 (a) and Tlr7 (b) exon3 with p < 0.05; the blue line is normalized dN-dS calculated in SLAC (Datamonkey); blue arrows-up - sites under positive selection detected by SLAC; black arrows-down - sites under positive selection detected by MEME (Datamonkey); blue full circles - sites under negative selection detected by SLAC. ECD - extracellular domain; LBR - ligand binding region; TD - transmembrane domain; TIR - TIR domain; ICD - intracellular domain; ICD-DP - distal part of intracellular domain.Back to article page