Figure 5
From: Phage-induced diversification improves host evolvability
Sensitivity of bacterial adaptation on rugged-slope landscapes to presence and specificity of coevolving phage. Rows from top-to-bottom show increasing ruggedness (decreasing span). In each row, plots show: Left: Example of adaptive landscape, plotting maximum growth rate (δγ) as a function of genotype (blue solid line) and the growth rate of the initial bacterial genotype (black dashed line). Middle: Frequency distribution of highest maximum growth rates in final populations for bacteria evolving alone. Right: Frequency distribution of highest maximum growth rates in final populations for bacteria coevolving with phage, as a function of specificity of phage (s). See text for details of method. Ensemble sizes {35,33,20,20} for span={1,3,5,7} respectively. Parameter settings as Table 1 except for manipulated s, M B =M V =10−5and V init =0 for no-phage treatments.