Skip to main content
Figure 2 | BMC Evolutionary Biology

Figure 2

From: Analyses of the radiation of birnaviruses from diverse host phyla and of their evolutionary affinities with other double-stranded RNA and positive strand RNA viruses using robust structure-based multiple sequence alignments and advanced phylogenetic methods

Figure 2

Schematic representation of the genomic organization of different dsRNA and +sRNA viruses. The polyprotein RBV ORF encompasses most of the genome segment A and contains the pVP2-VP4-VP3 sequence. The cleavage sites of the VP4 protease are indicated by vertical lines and their location is given by the P1/P1’ amino acid number. pVP2 is the VP2 capsid protein precursor while VP3 acts as a ribonucleoprotein that is associated to the genomic RNA. No additional open reading frame was evidenced in this segment in contrast to what is observed in other birnaviruses. The second genomic segment encodes VP1, the RNA-dependent RNA polymerase. B- Percentage of amino acid identity between the RBV proteins and their birnavirus homologs. C- Genetic organization of the double-stranded and positive strand RNA viruses used in this study. Shown are selected conserved domains of replicative and capsid proteins of birnaviruses (RBV, IBDV and others), TaV/EeV (Thosea asigna virus/Euprosterna elaeasa virus), DAV (Drosophila A virus), NβV (Nudaurelia β virus) and HaSV (Helicoverpa armigera stunt virus), FHV (Flock house virus), FMDV (Foot-and-mouth disease virus), Norwalk virus, HCV (Hepatitis C virus) and BVDV (bovine viral diarrhea virus), and phage Φ6. The conventional replicases are indicated with vertical hatched bars while permuted RdRp are represented with slanting bars.

Back to article page

BMC Ecology and Evolution

ISSN: 2730-7182

Contact us