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Figure 4 | BMC Evolutionary Biology

Figure 4

From: Evolution of the myosin heavy chain gene MYH14 and its intronic microRNA miR-499: muscle-specific miR-499 expression persists in the absence of the ancestral host gene

Figure 4

Medaka miR-499 characteristics. (A) Comparison of the flanking and related sequences of torafugu MYH14-1 (MYH M5 ) with zebrafish MYH14-1 and medaka miR-499. Highly conserved (>75%) regions between the two sequences are indicated by red-shaded peaks. Several highly conserved regions were identified at the MYH14/miR-499 5′-flanking and intron, as shown in blue boxes. (B) Putative secondary structures of mirtron (Caenorhabditis elegans miR-62) and miR-499.

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