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Figure 1 | BMC Evolutionary Biology

Figure 1

From: Evolution of the myosin heavy chain gene MYH14 and its intronic microRNA miR-499: muscle-specific miR-499 expression persists in the absence of the ancestral host gene

Figure 1

Genomic organization of MYH14 and miR-499 in various vertebrates. Orthologous genes are connected by solid and dotted lines. Genes displayed above the midline are in forward strands (+ orientation, from left to right), whereas those displayed below are in reverse strands (− orientation, from right to left). MYH14 and miR-499 paralogs found in one species are distinguished by numbers (see Table 1). Abbreviations used: Chr, chromosome; TRPC4AP, transient receptor potential cation channel, subfamily C, member 4 associated protein; EDEM2, ER degradation enhancer, mannosidase alpha-like 2; SLA2, Src-like-adaptor 2; NDRG3, N-myc downstream regulated family member 3; PHF20, PHD finger protein 20; SULF2, sulfatase 2.

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