Figure 1From: Structural and evolutionary adaptation of rhoptry kinases and pseudokinases, a family of coccidian virulence factorsPhylogeny of rhoptry kinase subfamilies. Predicted or known active kinases are labeled in bold text, and kinases that may have a noncanonical catalytic mechanism are marked with an asterisk. Newly proposed ROPK subfamilies are labeled in italic text. The clade indicated in red contains the ROPK subfamilies with a homologous N-terminal extension to the kinase domain (NTE). The clade in green is specific to E. tenella. The divergent “ROPKL” clade is shown in blue. Branch labels indicate bootstrap support. The grid along the right side indicates the species in which each subfamily appears: T. gondii (Tg), N. caninum (Nc), S. neurona (Sn) and E. tenella (Et).Back to article page