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Table 1 Distribution of polymorphic mutations in individual viruses isolated from bacteriophage Qβ populations evolved in the presence of AZC

From: Evolution at increased error rate leads to the coexistence of multiple adaptive pathways in an RNA virus

Nt1

1520

1604

2059

2277

2378

2384

2471

2982

3413

3545

3582

3879

3945

3989

4006

Wt2

U

C

C

A

C

C

C

A

C

C

U

C

G

U

A

Population Qβ-AZC(t60)3

C1

C

G

.

.

.

.

.

G

U

.

.

.

A

C

.

C2

C

.

.

.

.

.

.

G

.

.

.

.

A

C

.

C3

C

.

.

.

.

.

.

G

.

.

.

.

A

C

.

C4

C

G

.

.

.

.

G

G

.

.

.

.

A

C

.

C5

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

C6

.

.

.

.

.

.

.

.

G

.

.

.

.

.

G

C7

.

.

.

G

G

.

.

.

.

.

.

.

.

.

.

C8

.

.

.

.

.

G

.

.

.

.

.

.

.

.

.

C9

.

.

.

.

.

G

G

.

.

.

.

.

.

.

.

C10

.

.

.

.

.

.

.

.

.

.

.

.

.

C

.

Population Qβ-AZC(t70)3

C1

C

.

.

.

.

.

.

G

.

.

.

.

A

C

.

C2

C

.

G

.

.

.

.

G

.

.

.

.

A

C

.

C3

C

.

.

.

.

G

.

G

G

.

.

.

A

C

.

C4

.

.

.

.

.

.

.

.

.

.

C

.

.

.

.

C5

.

.

.

.

.

.

G

.

.

.

C

.

.

.

.

C6

.

.

.

.

.

.

.

.

G

.

C

.

A

C

.

C7

.

.

G

.

.

G

.

.

G

.

.

.

.

.

.

C8

.

.

.

.

.

.

.

.

G

.

.

.

.

.

.

C9

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

C10

.

.

.

.

.

.

G

.

.

.

.

G

.

.

.

Population Qβ-AZC(t90)3

C1

C

.

.

.

.

.

.

G

.

.

.

.

A

C

.

C2

C

G

.

.

.

.

G

G

.

A

.

.

A

C

G

C3

C

.

G

G

G

.

.

G

.

.

.

.

A

C

.

C4

C

G

.

.

.

.

.

G

.

A

.

.

A

C

G

C5

C

.

G

.

.

U

.

G

.

.

.

.

A

C

.

C6

C

.

G

G

.

.

G

G

.

.

.

.

A

C

.

C7

C

.

.

G

.

.

.

G

.

A

.

G

A

C

.

C8

C

G

G

.

.

.

G

G

G

A

.

.

A

C

G

C9

.

.

.

.

G

.

.

.

.

.

C

G

.

.

.

C10

.

.

.

.

G

.

.

.

.

.

C

.

.

.

G

C11

.

.

G

G

.

U

.

.

G

.

C

.

A

C

.

C12

.

.

.

G

.

G

.

.

.

.

.

.

.

.

.

C13

.

G

.

.

G

U

.

.

.

.

.

.

.

.

.

C14

C

.

.

G

.

G

.

.

.

.

.

.

A

.

.

C15

.

.

.

.

.

.

.

.

G

.

.

G

A

C

.

  1. 1Nucleotide positions where polymorphisms were detected.
  2. 2Nucleotides present at the positions indicated in the wild type virus.
  3. 3Nucleotides present at the positions indicated in the virus clones (indicated as Cx, where x is a number arbitrarily assigned) isolated from that populations. The region sequenced comprises from nucleotide 1485 to nucleotide 4028.
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BMC Ecology and Evolution

ISSN: 2730-7182

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