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Table 1 Summary of relevant results: Loci with extreme patterns of differentiation between continental groups. Loci showing extreme gene-level FST p-value after Bonferroni multiple comparison correction is applied taking into account the number of continental groups and the two methods applied

From: Distribution of events of positive selection and population differentiation in a metabolic pathway: the case of asparagine N-glycosylation

Sub-pathway Gene Continental Group p-value Corrected p-values
Branching 1 MAN2A2 CSASIA 3 × 10-12 4.2 × 10-11
  MGAT3 CSASIA 2 × 10-8 2.8 × 10-7
Branching 2 B4GALT2 MENA 2 × 10-7 2.8 × 10-6
  MGAT4A EUR 3 × 10-6 4.2 × 10-5
   EASIA 3 × 10-6 4.2 × 10-5
  ST3GAL4 SSAFR 3 × 10-7 4.2 × 10-6
  ST8SIA3 EUR 2 × 10-7 2.8 × 10-6
  ST8SIA6 CSASIA 3 × 10-6 4.2 × 10-5
Substrates DPM1 MENA 3 × 10-8 4.2 × 10-7
  DPM3 CSASIA 2 × 10-24 2.8 × 10-23
  PMM1 EASIA 8 × 10-7 1.1 × 10-5
  1. Populations were grouped as following: SSAFR, MENA, EUR, CSASIA, EASIA, OCE and AME standing respectively for Sub-Saharan Africa, Middle East-North Africa, Europe, Central South Asia, East Asia, Oceania and America.