Table 1 Summary of relevant results: Loci with extreme patterns of differentiation between continental groups. Loci showing extreme gene-level FST p-value after Bonferroni multiple comparison correction is applied taking into account the number of continental groups and the two methods applied
Sub-pathway | Gene | Continental Group | p-value | Corrected p-values |
|---|---|---|---|---|
Branching 1 | MAN2A2 | CSASIA | 3 × 10-12 | 4.2 × 10-11 |
|  | MGAT3 | CSASIA | 2 × 10-8 | 2.8 × 10-7 |
Branching 2 | B4GALT2 | MENA | 2 × 10-7 | 2.8 × 10-6 |
|  | MGAT4A | EUR | 3 × 10-6 | 4.2 × 10-5 |
|  |  | EASIA | 3 × 10-6 | 4.2 × 10-5 |
|  | ST3GAL4 | SSAFR | 3 × 10-7 | 4.2 × 10-6 |
|  | ST8SIA3 | EUR | 2 × 10-7 | 2.8 × 10-6 |
|  | ST8SIA6 | CSASIA | 3 × 10-6 | 4.2 × 10-5 |
Substrates | DPM1 | MENA | 3 × 10-8 | 4.2 × 10-7 |
|  | DPM3 | CSASIA | 2 × 10-24 | 2.8 × 10-23 |
|  | PMM1 | EASIA | 8 × 10-7 | 1.1 × 10-5 |