Adaptive evolution by recombination is not associated with increased mutation rates in Maize streak virus

Table 1 Step-down multiple testing corrected binomial probability support for strand-specific nucleotide mutation biases in MSV and TYLCV (Two-tailed probabilities in brackets)

Mutation	Recombinant data combined^a	VWMPCPLIRMat	MSV:MatA	MSV:VW	MSV data combined^b	MSV data combined^c	TYLCV^d
A → G : T → C	2 : 2	2 : 1	4 : 0	1 : 1	9 : 4	16 : 6	8 : 22
Binomial probability	0.750 (1.000)	1.000* (1.000*)	0.252 (0.500)	0.500 (1.000*)	0.174 (0.801)	0.054 (0.157)	0.020 (0.064)
A → C : T → G	2 : 0	1 : 1	3 : 1	0 : 5	6 : 6	11 : 10	10 : 12
Binomial probability	0.250 (1.000)	1.000 (1.000*)	0.500 (1.000*)	0.124 (0.252)	0.904 (1.000)	0.168 (1.000)	0.154 (0.832)
G → T : C → A	8 : 2	3 : 1	1 : 2	1 : 2	13 : 7	29 : 9	46 : 30
Binomial probability	0.132 (0.436)	1.000 (1.000*)	0.375 (1.000)	0.760 (1.000*)	0.222 (0.526)	0.004 (0.007)	0.051 (0.254)
G → A : C → T	4 : 11	1 : 3	3 : 6	5 : 6	13 : 26	18 : 30	48 : 55
Binomial probability	0.168 (0.354)	1.000 (1.000*)	0.492 (1.000*)	0.675 (1.000*)	0.060 (0.212)	0.052 (0.222)	0.124 (1.108)

^aRecombinant genomes obtained using the MatMPCPVW + VWMPCPMat and MatMPCPLIRVW + VWMPCPLIRMat parental chimaeric MSV genomes [47].
^bData combined using values from this study only.
^cData combined using values from this study and from van der Walt et al.[29].
^dData obtained from Martin et al. [48]*The calculated step-down multiple tested corrected p-values greater than 1 are simply represented as having a p-value of 1.

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