Figure 2
From: Massive expansion of the calpain gene family in unicellular eukaryotes
Eukaryotic calpain phylogeny reconstructed by Bayesian inference of the CysPc domain sequence. Several lineages that share similar domain combinations are collapsed into major clades for details of species names and protein domains, see Figure 1 and Additional file 2: Figure S1. Typical domain organization is schematically displayed in each clade. The names of domains are shown on the bottom with different symbols. Only the genus names of sampled taxa are listed. The clades representing four proposed ancestral domain architectures are color-coded (i.e. CysPc in dark brown, CysPc-C2L in blue, MIT-CysPc-C2L in light green and TML-CysPc-C2L in dark green). For each node, statistical support values are marked (numbers from left to right: Bayesian posterior probabilities (PP) inferred under LG /CAT models and maximum-likelihood bootstraps (% BP) inferred using PROTGAMMALG model). Dashes ‘-’ indicate support values < 50% BP or 0.5 PP.