Figure 2From: Pathogen-induced Caenorhabditis elegans developmental plasticity has a hormetic effect on the resistance to biotic and abiotic stressesC. elegans signaling pathways involved in developmental modulation of longevity. Survival of C. elegans mutants to E. coli 536 pathogen following development on strains 536 (536/536) or OP50 (OP50/536) and life through OP50 control (OP50/OP50). (A &B) C. elegans daf-16 mutants allele mu86 (536/536 n = 80, OP50/536 n = 80, and OP50/OP50 n = 80, independent repeats N = 4) and mgDf50 (536/536 n = 65, OP50/536 n = 56, and OP50/OP50 n = 61, N = 3), (C) C. elegans dbl-1 mutant (536/536 n = 127, OP50/536 n = 124, and OP50/OP50 n = 88, N = 4), and (D) C. elegans pmk-1 mutant (536/536 n = 80, OP50/536 n = 78, and OP50/OP50 n = 77, N = 8). No differential survival of daf-16 and dbl-1 nematodes to E. coli 536 based on developmental conditions was observed, while a small but statistically significant difference in survival to E. coli 536 strain was observed for C. elegans pmk-1 mutant depending on developmental conditions. Graphed: ns: not significant, *: p < 0.05, **: p < 0.01, ***: p < 0.001, ****: p < 0.0001.Back to article page