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Table 2 Phylogenetic signal in chemistry and biological activity determined using Fritz and Purvis’s[57]D metric (see Materials and Methods for details)

From: Can phylogeny predict chemical diversity and potential medicinal activity of plants? A case study of amaryllidaceae

a) Chemical components

Alkaloid group

D

P (D = 1)

P (D = 0)

Crinine

0.6768

0.021

0

Galanthamine

0.549

0

0.009

Lycorine

0.77

0.018

0

Galanthindole

1.091

0.621

0.011

Homolycorine

0.769

0.021

0

Montanine

0.572

0.002

0.01

Tazettine

0.852

0.094

0

b) Biological activity

Measure

D

P (D = 1)

P (D = 0)

AChE

0.679

0.004

0.001

SERT

0.634

0.037

0.044

  1. D is equal to 1 if the observed chemical component has a random distribution (i.e. no phylogenetic signal). D is equal to 0 if the component is distributed exactly as would be predicted under a Brownian motion model of gradual divergent evolution (i.e. strong phylogenetic signal). P values represent the probability that the observed D value is equal to 1 or 0, respectively (P >0.05 indicates that the observed value is not significantly different from these values).
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BMC Ecology and Evolution

ISSN: 2730-7182

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