Figure 2From: The mammalian PYHIN gene family: Phylogeny, evolution and expressionPredicted protein domain organisation derived from cDNA sequences for human and mouse and predicted genes for rat. Pyrin domains are indicated by stippled boxes, and the HIN domain subtypes (A, B or C) are shown. Only a single splice variant is shown for human IFI16 and IFIX, with complete details summarised previously [22]. Mouse p203 also has known splice variants [63]. Regions of sequence similarity among mouse proteins and the relationship between mouse and rat proteins are summarised in Additional Files 1 and 6.Back to article page