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Figure 2 | BMC Evolutionary Biology

Figure 2

From: The mammalian PYHIN gene family: Phylogeny, evolution and expression

Figure 2

Predicted protein domain organisation derived from cDNA sequences for human and mouse and predicted genes for rat. Pyrin domains are indicated by stippled boxes, and the HIN domain subtypes (A, B or C) are shown. Only a single splice variant is shown for human IFI16 and IFIX, with complete details summarised previously [22]. Mouse p203 also has known splice variants [63]. Regions of sequence similarity among mouse proteins and the relationship between mouse and rat proteins are summarised in Additional Files 1 and 6.

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