Likelihood phylogeny of PWWP containing proteins in A. thaliana and A. lyrata. figure 4 PWWP-domain sequences with the highest BLAST scores were used to generate the Maximum Likelihood phylogenetic tree. The distinct PWWP-domain subgroups (as discussed in the main text) are indicated by numbers and shaded in different colors. Domain names and representative domain architecture are shown for the major PWWP-domain protein families. Species abbreviations correspond to A. thaliana (At) and A. lyrata (Alyrata). The branch length is proportional to the number of substitutions per site. Numbers in red correspond to the branch support values. The FATC and the PIKKc_ATM domains in the ATM proteins represent the FRAP, ATM, TRRAP C-terminal domain and the phosphoinositide 3-kinase-related protein kinase_Ataxia telangiectasia mutated (ATM), catalytic domain, respectively.