Table 2 Principal Component Analysis on Evolutionary Rate (ω) with (a) Gene Level Predictors, (b) Transcript Level Predictors, (c) Protein Level Predictors.
From: Evolutionary dynamics of human autoimmune disease genes and malfunctioned immunological genes
a. Gene Level Predictors | ||
|---|---|---|
Principal Component1 | Principal Component2 | |
Percent of the total variance Correlation Coefficient (Spearman's ρ) with ω | 27.502 -0.061** | 21.912 0.113** |
Major Contributing Factor in PCA1 | ||
Paralogs Number Recombination Rate | 0.789 0.805 | --- --- |
Major Contributing Factor in PCA2 | ||
Single Nucleotide Polymorphism Copy Number Variation | --- --- | 0.995 0.713 |
a. Transcript Level Predictors | ||
Percent of the total variance Correlation Coefficient (Spearman's ρ) with ω | 39.071 -0.161** | |
Major Contributing Factor in PCA1 | ||
m-RNA abundance Alternatively Spliced Exons Disorderness | 0.702 0 0.688 0.446 | |
c.Protein Level Predictors | ||
Percent of the total variance Correlation Coefficient (Spearman's ρ) with ω | 69.095 -0.321*** | |
Major Contributing Factor in PCA1 | ||
Fraction of Phosphorylation Residues Proportion of Buried Residues | 0.557 0.743 | |