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Table 1 Tests of parallel and convergent evolution of PGRPs.

From: Evolutionary origin of peptidoglycan recognition proteins in vertebrate innate immune system

Species

n

P

Site positions

A. Parallel changes

Ā Ā Ā 

Pig-S & Cow-S

3

0.003

2, 78, 113

Frog-S2 & Rat-S

2

0.02*

34, 77

Rainbow trout-L1 & stickleback-L

3

0.006

45, 52, 120

Rat-Ia-C & Rat-S

1

0.03

77

Fugu-L & Pig-L

1

0.04*

89

Chicken-L & Salmon-L

1

0.049

108

Rainbow trout-L1 & Zebrafish-L1

3

0.03

45, 100, 114

Stickleback-L & Rat-Ia-C

1

0.048

125

B. Convergent changes

Ā Ā Ā 

Human-Ib-N & Rat-Ib-C

1

0.029

5

Cow-S & Frog-L

2

0.0071

12, 125

Pig-S & Frog-S1

2

0.002

15, 123

Fugu-L & Hagfish-S

2

0.007

21, 78

Frog-S2 & Rat-S

1

0.02*

100

Mouse-L & Killifish-L

1

0.02

38

Mouse-L & Rat-Ia-N

1

0.05

38

Rat-Ia-N & Killifish-L

1

0.035

38

Carp-L & Hagfish-S

2

0.007

41, 140

Mouse-Ia-N & Pig-S

1

0.016

43

Mouse-S & Mouse-Ib-C

1

0.014

52

Rat-Ib-N & Pig-S

1

0.02

54

Rainbow trout-L1 & Mouse-Ia-N

1

0.02

77

Fugu-L & Pig-L

1

0.04*

78

Pig-L & Human-Ia-C

1

0.02

96

Rat-S & Rainbow trout-L1

1

0.05

100

Mouse-L & Zebrafish-L1

1

0.048

101

Rat-S & Cow-S

1

0.015

101

Human-S & Salmon-L

1

0.008

108

Pig-S & Salmon-L

1

0.008

108

Human-S & Chicken-L

2

0.007

105, 108

Frog-S1 & Mouse-Ia-C

1

0.038

109

Mouse-L & Mouse-Ia-N

1

0.02

117

Human-Ia-C & Rat-S

1

0.03

121

Carp-L & Fugu-L

1

0.021

123

Zebrafish-L2-N & Medaka-L1

1

0.009

145

  1. n = Number of sites where parallel or convergent evolution occurred.
  2. P = Observed probability of parallel or convergent change
  3. * = Observed probability of parallel and convergent change
  4. Internodal branches are omitted.