Figure 4

Schematic representations of examples of sites under selection and conserved domains in MCPs (A, B, and C) and adhesins (D). In the upper parts of each panel the sequence alignments of proteins are presented for parts containing sites under selection. The orthologous sequences collected from genome sequences of Xcv85-10, Xac306, and XapCFBP4834 were aligned using ClustalW according to the translated amino-acid sequences, manually performed using BIOEDIT. Sites that were found under selection are highlighted by green frames. In the lower parts of the panels, conserved domains are represented. HAMP: Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase domain. HAMP is a signalling domain that occurs in a wide-variety of signalling proteins. TarH superfamily: Taxis toward Aspartate and Related amino acids and Homologs. MA: Methyl-accepting chemotaxis-like domain (chemotaxis sensory transducer), thought to undergo reversible methylation in response to attractants or repellents during bacterial chemotaxis. NarQ: signal transduction histidine kinase, nitrate/nitrite-specific. Annotation bars coloured in grey refer to multi-domains that are excluded from domain-domain neighbouring. In the D panel, green, blue, purple, and orange ovals symbolised TAT signal, Hep-Hag motif, HIM motif and YadAlike, C-terminal domain, respectively.