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Table 4 Genetic distance to a new genotype network decreases with increasing penetrance

From: Phenotypic plasticity can facilitate adaptive evolution in gene regulatory circuits

N

c

d

Spearman's ρ

p-value

 

8

0.4

0.25

-0.268

< 2.2 × 10-16

 
  

0.125

-0.211

< 2.2 × 10-16

 
 

0.3

0.25

-0.218

< 2.2 × 10-16

 

16

0.35

0.25

-0.293

< 2.2 × 10-16

 
 

0.25

0.125

-0.263

< 2.2 × 10-16

 
  

0.25

-0.306

< 2.2 × 10-16

 

20

0.3

0.25

-0.26

< 2.2 × 10-16

 
 

0.2

0.1

-0.269

< 2.2 × 10-16

 
  

0.25

-0.33

< 2.2 × 10-16

 
  

0.5

-0.4

< 2.2 × 10-16

 
 

0.1

0.25

-0.23

< 2.2 × 10-16

 
  1. Data for each parameter combination is based on 104 different circuits and on the non-parametric rank correlation coefficient Spearman's ρ [76].