Emergence and evolution of the glycoprotein hormone and neurotrophin gene families in vertebrates

Table 1 Gph-related gene paralogous gene sets

Paralogous gene set	Human	Lizard	Chicken
[LHβ]	chr. 19: 49-51, 56-59 Mb	chr. 6: 79-81 Mb	not found
	chr. X: 47-56, 153-154 Mb	chr. 1: 205 Mb, chr. 2: 68-90 Mb	not found
	chr. 7: 77-140 Mb
[GPHβ-Ghost]	chr. 10: 5-15 Mb	chr. 5: 0-100 Mb	chr. 1: 0-80 Mb
	chr. 12: 0-124 Mb
	chr. 22: 33-51 Mb
[FSHβ]	chr. 3: 0-15, 47-73, 125-129Mb	chr. 2: 147-191 Mb	chr. 12: 1-20 Mb
	chr. 11: 0-48, 68-70 Mb	chr. 1: 45-76 Mb	chr. 5: 0-23 Mb
[TSHβ]	chr. 1: 111-115/200-210 Mb	chr. 4: 105-140 Mb	chr. 26: 0-5 Mb
	chr. 6: 35-42 Mb
	chr. 1: 210-245 Mb
[GPHα]	chr. 2: 18-68 Mb	chr. 1: 127-143, 216-264 Mb	chr. 3: 2-80 Mb
	chr. 20: 6-25 Mb
	chr. 6: 40-44/88/152/170 Mb
[GPB5]	chr. 14: 27-106 Mb	chr. 1: 0-42 Mb	chr. 5: 26-62 Mb
	chr. 15: 33-43 Mb
[GPA2]	chr. 11: 61-67 Mb	unplaced	not found
[GP-Ghost]	chr. 19: 36-49 Mb	unplaced	not found

Observed boundaries of gph-related gene-containing paralogous gene sets in human, lizard and chicken genomes are given in megabase pairs (Mb) on the relevant chromosome (chr.). Some of the paralogous gene sets are scattered over several chromosomes (See Additional files 7 and 9 for the gene composition of each paralogous gene sets).

ISSN: 2730-7182