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Figure 9 | BMC Evolutionary Biology

Figure 9

From: Emergence and evolution of the glycoprotein hormone and neurotrophin gene families in vertebrates

Figure 9

Comparative genomic environment of gpa2 and gpb5. Genes are given with, underneath, their position in megabase pairs from the p end of each chromosome (chr.) in human and zebrafish (zebra) (see Additional file 10 for details and links to Ensembl website). Amphioxus (Amphi) homologues are given with the scaffold number (version 2) on which they are located. Names are after Ensembl in the human genome except for amphioxus homologues, which were reduced. Duplicated chromosome fragments in zebrafish are indicated with brackets. Due to rearrangements, the zebrafish gpb5b environment is scattered among chr. 13 and 17 whereas its FSGD driven duplicated environment is on chr. 20. Human GPB5 is orthologous to zebrafish GPB5b, whereas zebrafish GPB5a environment is orthologous to that of human GPA2.

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