Data were showed for the six paralogous groups, as published in mouse , zebrafish , medaka  and dogfish (this study) (expression patterns of co-orthologs such as zebrafish dlx2a and dlx2b were added up). Species initials are indicated when positive expression has been published in the epithelial (E) or mesenchymal (M) compartments in the different stages. See legend of Figure 2 for abbreviations of developmental stages; m: mouse, Mus musculus; o: medaka, Oryzias latipes; d: zebrafish, Danio rerio; s: dogfish, Scyliorhinus canicula; -: no expression detected. Expression of dogfish Dlx2 that was observed only in scale buds is indicated in brackets, expression of medaka dlx5a observed only in oral teeth is indicated in brackets. Bold shows characteristics conserved among all gnathostomes, italics indicate characteristics possibly lost in mouse.