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Table 3 Divergence times of major splits in the malarial phylogeny as estimated by MultiDivTime and BEAST

From: Timing the origin of human malarias: the lemur puzzle

Calibrations: node56, min = 6, max = 8; ABSMAX = 91   MultiDivTime (MDT) Beast  
Divergence Node Node Age (Mya) 95% CrI Node Age (Mya) 95% CrI cCrIs
Origin of Southerm Asia Macaca species 55 4.55 3.53, 5.64 3.62 2.76, 4.60 2.76-5.64
Split P. cynomolgi-P. vivax 52 2.50 1.77, 3.39 2.09 1.31, 2.90 1.31- 3.39
Origin of Catarrhini parasite (excluding P. ovale) 57 14.20 11.22, 17.48 13.52 10.26, 17.29 10.26-17.48
Split Papio-Macaca 56 7.39 6.26, 7.98 6.79 6.00, 7.80 6.00-7.98
Lorisiforms-Catarrhini parasite 58 16.31 12.75, 20.38 15.66 12.14, 19.67 12.14-20.38
Radiation Lorisiforms parasite 42 12.31 9.19, 16.05 12.41 9.52, 15.78 9.19-16.05
Radiation Apes parasite 35 9.07 6.12, 12.9 9.80 6.97, 13.06 6.12-13.06
Radiation Rodents parasite 38 9.57 6.62, 13.36 7.61 5.30, 10.34 5.30-13.36
Split P. falciparum-P. reichenowi 33 2.96 1.75, 4.71 3.42 2.25, 4.67 1.75-4.71
Origin of P. falciparum 31 0.27 0.03, 0.67 0.25 0.10, 0.43 0.03-0.67
Origin of Plasmodium in mammals 60 24.97 19.04, 32.27 21.56 16.46, 26.86 16.46-32.27
Calibrations: node56, min = 6, max = 14.3; ABSMAX = 91       
Origin of Southerm Asia Macaca species 55 7.62 5.13, 9.83 3.98 2.65, 5.89 2.65-9.83
Split P. cynomolgi-P. vivax 52 4.28 2.68, 6.09 2.30 1.22, 3.58 1.22-6.09
Origin of Catarrhini parasite (excluding P. ovale) 57 22.53 15.83, 28.79 14.76 9.86, 21.82 9.86-28.79
Split Papio-Macaca 56 12.41 8.83, 14.24 7.46 6.00, 10.71 6.00-14.24
Lorisiforms-Catarrhini parasite 58 25.48 17.90, 33.14 17.11 11.71, 24.94 11.71-33.14
Radiation Lorisiforms parasite 42 18.99 12.82, 25.63 13.60 9.20, 19.91 9.20-25.63
Radiation Apes parasite 35 13.92 8.86, 20.10 10.83 6.76, 16.36 6.76-20.10
Radiation Rodents parasite 38 15.12 9.58, 21.72 8.32 5.10, 12.60 5.10-22.71
Split P. falciparum-P. reichenowi 33 4.66 2.61, 7.54 3.77 2.21, 5.84 2.21-7.54
Origin of P. falciparum 31 0.42 0.04, 1.08 0.28 0.10-0.50 0.01-1.08
Origin of Plasmodium in mammals 60 37.78 26.24, 50.26 23.73 16.18, 35.02 16.18-50.26
Calibrations: node56, min = 6, max = 14.3; node57, min = 23.5; ABSMAX = 91       
Origin of Southerm Asia Macaca species 55 8.28 6.50, 10.23 6.75 5.12, 8.42 5.12-10.23
Split P. cynomolgi-P. vivax 52 4.66 3.30, 6.29 3.93 2.50, 5.43 2.50-6.29
Origin of Catarrhini parasite (excluding P. ovale) 57 25.70 23.58, 30.09 26.27 23.5, 31.12 23.50-31.12
Split Papio-Macaca 56 13.41 11.58, 14.27 12.09 9.80, 14.30 9.80-14.30
Lorisiforms-Catarrhini parasite 58 28.91 25.17, 34.60 29.83 24.97, 35.72 24.97-35.72
Radiation Lorisiforms parasite 42 21.49 17.21, 26.88 23.59 18.93, 28.79 17.21-28.79
Radiation Apes parasite 35 15.78 11.29, 21.64 18.37 12.79, 24.03 11.29-24.03
Radiation Rodents parasite 38 17.20 12.46, 23.08 14.20 9.96, 18.89 9.96-23.08
Split P. falciparum-P. reichenowi 33 5.27 3.18, 8.23 6.39 4.27, 8.64 3.18-8.64
Origin of P. falciparum 31 0.48 0.04, 1.22 0.48 0.19, 0.81 0.04-1.22
Origin of Plasmodium in mammals 60 42.72 35.24, 53.03 40.97 32.89, 50.18 32.24-53.03
  1. Point time estimates and their associated 95% credibility intervals (CrIs) are shown in millions of years (Mya). Combined CrIs are also shown (cCrIs). Node numbers are listed in additional file 4. The absolute maximum for the ingroup root node (ABSMAX) was set at 91 Mya (see Methods for more details).