Study of Sylvilagusrabbit TRIM5α species-specific domain: how ancient endoviruses could have shaped the antiviral repertoire in Lagomorpha

Table 2 Positively-selected codon positions in the Lagomorpha TRIM5α deduced protein sequences

Codon^a	Normalized E [dN-dS]	Posterior Probability	Bayes Factor	Region	Orcu^b	Leeu	Legr	Syba	Ocpr
3	0.30	1.00	795	-	S⁰	S⁰	S⁰	A ⁰	S⁰
148	0.29	0.99	224	CC	N⁰/K⁺	N⁰	N⁰	H^0/+	K⁺
196	0.29	0.99	179	CC	E^-	G ⁰	G ⁰	E^-	M ⁰
279	0.30	1.00	1913	-	I ⁰	T⁰	I ⁰	I ⁰	A ⁰
288	0.29	0.99	178	-	M ⁰	V ⁰	V ⁰	M ⁰	N⁰
327	0.30	1.00	6611	v1	H^0/+/Q⁰	Q⁰	Q⁰	K⁺	F ⁰
329	0.30	1.00	578	v1	R⁺	H^0/+	H^0/+	Q⁰	G ⁰
330	0.30	1.00	35572	v1	L ⁰	G ⁰	G ⁰	P ⁰	N⁰
331	0.30	0.99	405	v1	N⁰	S⁰	S⁰	S⁰	V ⁰
332	0.30	1.00	33711	v1	L ⁰	L ⁰	L ⁰	F ⁰	S⁰
334	0.30	1.00	5055	v1	S⁰	L ⁰	L ⁰	P ⁰	G ⁰
336	0.30	0.99	294	v1	S⁰	K⁺	K⁺	N⁰	K⁺
341	0.30	1.00	483	v1	F ⁰	C ⁰	C ⁰	R⁺	L ⁰
342	0.30	1.00	574	v1	R⁺	Q⁰	Q⁰	Q⁰	T⁰
347	0.30	0.99	320	v1	T⁰	I ⁰	I ⁰	T⁰	L ⁰
348	0.30	1.00	691	v1	R⁺	K⁺	K⁺	G ⁰	T⁰
391	0.30	1.00	3822	v2	T⁰	I ⁰	I ⁰	T⁰	Q⁰
396	0.30	0.99	438	v2	Y⁰	Y⁰	Y⁰	F ⁰	P ⁰
399	0.30	0.99	368	v2	V ⁰	F ⁰	F ⁰	A ⁰	G ⁰
415	0.28	0.98	134	v3	I ⁰	N⁰	N⁰	N⁰	G ⁰
434	0.30	0.99	432	v3	P ⁰	P ⁰	P ⁰	L ⁰	S⁰
457	0.29	0.99	217	-	K⁺	T⁰	T⁰	K⁺	V ⁰
464	0.30	0.99	416	-	S⁰	S⁰	S⁰	A ⁰	S⁰
469	0.30	0.99	418	-	S⁰	A ⁰	A ⁰	S⁰	S⁰
480	0.30	1.00	639	-	H^0/+	Q⁰	Q⁰	Q⁰	T⁰

European rabbit (Orcu), European brown hare (Leeu), Iberian hare (Legr), brush rabbit (Syba) and American pika (Ocpr).
^a Codon positions are numbered according to the alignment in Figure 1.
^b Single amino acid = same for both Orcu subspecies, Oryctolagus cuniculus cuniculus (Orcucu) and Oryctolagus cuniculus algirus (Orcual); Two amino acids divided by "/" = Orcucu amino acid/Orcual amino acid
Codon physical-chemical properties are also represented: Underlined codon = non-polar amino acid; non-underlined codon = polar amino acid; ⁺ = positive amino acid; ^- = negative amino acid; ⁰ = neutral amino-acid.

ISSN: 2730-7182