From: Coevolution of amino acid residues in the key photosynthetic enzyme Rubisco
Species | Rubisco state | PDB | 3D-distance | Coevolving sites distance | Positively selected sites distance | Positively selected site/active site distance | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 |  |  | mean | median | st.dev. | mean | median | p-value# | Difference* | mean | median | p-value# | Difference* | mean | median | p-value# | Difference* |
Nicotiana tabacum | Activated | 4RUB | 31.38 | 29.66 | 14.34 | 28.14 | 26.66 | 6.7E-9 (1.8E-8) | 3.24 | 33.76 | 31.97 | 0.057 (0.036) | 2.38 | 28.50 | 26.23 | 0.144 (0.164) | 2.88 |
 | Unactivated | 1EJ7 | 31.44 | 29.86 | 14.24 | 27.5 | 25.6 | 5.6E-10 (6.9E-10) | 3.94 | 33.01 | 32.40 | 0.146 (0.094) | 1.57 | 27.97 | 25.28 | 0.099 (0.126) | 3.47 |
 | Average minimum |  | 28.76 | 27.13 | 13.58 | 25.27 | 22.77 | 1.8E-8 (6.1E-9) | 3.50 | 31.55 | 30.27 | 0.025 (0.019) | 2.78 | 26.18 | 24.02 | 0.156 (0.192) | 2.59 |
Spinacia oleracea | Activated | 8RUC | 31.48 | 29.77 | 14.37 | 28.21 | 26.56 | 1.1E-8 (1.3E-8) | 3.27 | 34.15 | 32.08 | 0.038 (0.025) | 2.62 | 28.74 | 26.38 | 0.156 (0.181) | 2.74 |
 | Unactivated | 1RCX | 31.24 | 29.54 | 14.26 | 27.97 | 26.23 | 8.5E-9 (1.1E-8) | 3.27 | 33.97 | 32.12 | 0.034 (0.022) | 2.73 | 28.51 | 26.09 | 0.155 (0.180) | 2.73 |
 | Average minimum |  | 31.22 | 29.53 | 14.26 | 27.96 | 26.23 | 9.3E-9 (8.2E-9) | 3.26 | 33.94 | 32.08 | 0.034 (0.023) | 2.72 | 28.50 | 26.09 | 0.156 (0.180) | 2.72 |