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Figure 2 | BMC Evolutionary Biology

Figure 2

From: The phylogenomic analysis of the anaphase promoting complex and its targets points to complex and modern-like control of the cell cycle in the last common ancestor of eukaryotes

Figure 2

Evolutionary history of APC/C subunits, adaptors/co-activators and main targets. We used a reference phylogenetic tree rooted in-between Unikonta and Bikonta [23] showing the relationships between the eleven major eukaryotic lineages for which complete (or nearly complete) genome sequences are available [56, 63, 64, 78]. Holozoa are representated by Capsaspora, Choanoflagellata and Metazoa (in pink); Fungi by Dikarya, Chytridiomycota and Microsporidia (in dark purple); Alveolata by Apicomplexa and Ciliata (in brown) and Plantae by Viridiplantae and Rhodophyta (in green). The completion status for each genome sequence is indicated: "C": complete, " A": draft assembly, "P": ongoing (accordingly the loss of some components inferred in the corresponding lineages should be confirmed when complete genome sequences are available). LECA (grey circle) represents the Last Eukaryotic Common Ancestor. Based on phylogenetic analyses, we inferred the time of appearance or loss of orthologues of APC/C subunits (dark blue), activators (light blue) and main targets (pink). For each lineage, protein gains and losses are indicated by green and red arrows, respectively.

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BMC Ecology and Evolution

ISSN: 2730-7182

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