Skip to main content
Figure 1 | BMC Evolutionary Biology

Figure 1

From: The phylogenomic analysis of the anaphase promoting complex and its targets points to complex and modern-like control of the cell cycle in the last common ancestor of eukaryotes

Figure 1

Schematic structure of the APC/C. The APC/C is divided in three parts: the structural complex composed of three subunits (in pink), the TPR arm made of nine proteins (in blue) and a second arm (the catalytic arm) made of three proteins (in green) interacting with the E2 protein (in purple) and the substrate (in grey). The activity and specificity of the APC/C is modulated by various adaptor/co-activators (in orange). The location of Apc14 (in black) remains uncertain. The presence of RING finger and Cullin conserved functional domains, and of TPR and WD repeats is indicated.

Back to article page