Table 1 Reference set of genes
From: Protein-based signatures of functional evolution in Plasmodium falciparum
P. falciparum gene | Other identifier | Product | Pf amino acids | P. chabaudi gene | Pc amino acids |
|---|---|---|---|---|---|
ATPases | Â | Â | Â | Â | Â |
PFA0300c | MAL1P1.52 | Vacuolar ATPase-coupled proton transport | 383 | PCHAS_020560 | 383 |
PFC0840w | PfATPase7 | Phospholipid transporting ATPase | 1864 | PCHAS_080610 | 1773 |
PFE0195w | PfATPase3 | Cation transporting ATPase | 2393 | PCHAS_110330 | 1904 |
PF07_0047 | None | Cell-division cycle ATPase | 1229 | PCHAS_122230 | 1106 |
PF08_0113 | None | Vacuolar proton transporting ATPase | 1053 | PCHAS_122440 | 957 |
PFI0240c | None | Cu2+- transporting ATPase | 2563 | PCHAS_041740 | 2128 |
PFL0590c | PfATPase4 | Non-SERCA type Ca2+-transporting ATPase | 1208 | PCHAS_020540 | 1468 |
PFL1125w | MAL12P1.225 | Phospholipid transporting ATPase | 1618 | PCHAS_144030 | 1601 |
Transporters | Â | Â | Â | Â | Â |
PFB0210c | PfHT1 | Hexose transporter | 504 | PCHAS_030470 | 505 |
PFB0465c | PF02_0097 | Monocarboxylate transporter | 457 | PCHAS_030940 | 456 |
PFE1185w | MAL5P1.237 | Metal transporter | 684 | PCHAS_123900 | 704 |
PFF0450c | MAL6P1.94 | Zn2+ or Fe2+ transporter | 361 | PCHAS_010830 | 338 |
PFF0170w | MAL6P1.38 | Calcium antiporter | 441 | PCHAS_010300 | 440 |
PFF1430c | MAL6P1.133 | Amino acid transporter | 606 | PCHAS_112780 | 617 |
PFI1295c | None | Monocarboxylate transporter | 529 | PCHAS_082700 | 507 |
PF11_0210 | None | Mg2+, Co2+ & Ni2+ channel | 529 | PCHAS_091640 | 435 |
PF11_0338 | PfAQP | Aquaglyceroporin | 258 | PCHAS_093040 | 258 |
MAL13P1.23 | None | CorA-like Mg2+ transporter | 468 | PCHAS_140460 | 491 |
PF13_0252 | PfNT1 | Nucleoside transporter | 422 | PCHAS_136470 | 414 |
PF14_0679 | None | Inorganic anion antiporter | 664 | PCHAS_133900 | 700 |
Glycolytic | Â | Â | Â | Â | Â |
PFF1155w | MAL6P1.189 | Hexokinase | 493 | PCHAS_112240 | 494 |
PF14_0341 | None | Glucose-6-phosphate isomerase | 579 | PCHAS_100870 | 578 |
PFI0755c | None | 6-Phosphofructokinase | 1418 | PCHAS_081620 | 1306 |
PF14_0425 | None | Fructose-bisphosphate aldolase | 369 | PCHAS_131180 | 369 |
PF14_0378 | None | Triosephosphate isomerase | 248 | PCHAS_130700 | 248 |
PFI1105w | PGK | Phosphoglycerate kinase | 416 | PCHAS_082320 | 416 |
PF11_0208 | None | Phosphoglycerate mutase | 250 | PCHAS_091620 | 250 |
PF10_0155 | None | Enolase | 446 | PCHAS_121500 | 446 |
PFF1300w | MAL6P1.160 | Pyruvate kinase | 511 | PCHAS_112510 | 511 |
PF13_0141 | PfLDH | L-lactate dehydrogenase | 316 | PCHAS_134470 | 316 |
DNA/RNA | Â | Â | Â | Â | Â |
PFB0730w | PF02_0151 | DEAD/DEAH box helicase | 1997 | PCHAS_031480 | 1404 |
PFC0805w | MAL3P6.20 | DNA-directed RNA polymerase II | 2457 | PCHAS_080680 | 2307 |
PFE0465c | MAL5P1.95 | RNA polymerase I | 2914 | PCHAS_110870 | 2570 |
PFE0715w | MAL5P1.144 | Asparagine-tRNA ligase | 1128 | PCHAS_111360 | 1084 |
PFF1095w | MAL6P1.201 | Leucyl tRNA synthase | 1447 | PCHAS_112120 | 1251 |
MAL7P1.145 | None | Mismatch repair protein pms1 | 1330 | PCHAS_020880 | 1094 |
PF13_0251 | None | DNA topoisomerase III | 710 | PCHAS_136460 | 676 |
PF14_0234 | None | DNA-directed DNA polymerase | 1236 | PCHAS_101890 | 989 |
PF14_0316 | None | DNA topoisomerase II | 1472 | PCHAS_101120 | 1460 |
PF14_0695 | None | DNA-directed RNA polymerase | 861 | PCHAS_134050 | 796 |