Figure 7
From: Protein-based signatures of functional evolution in Plasmodium falciparum
Conservation-hydrophilicity plot for amino acid variants associated with drug resistance or within drug-resistance regions. All mutations shown to be involved in drug resistance by transfection (22 nSNPs in CRT, DHFR and DHPS) or drug pressure studies (14nSNPs in cytochrome b, rpl4 and PfATPase4) are shown along with variants in chromosomal regions around CRT, DHFR and DHPS (see Figure 5).