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Figure 1 | BMC Evolutionary Biology

Figure 1

From: Histone variant innovation in a rapidly evolving chordate lineage

Figure 1

O. dioica histone gene complement. Histone clusters consist of 2-5 genes dispersed throughout the genome (loci given as roman numerals). Genes belonging to a given cluster were transcriptionally co-regulated and developmental expression profiles of the clusters are indicated with icons (key: H, hatching; ETP, early tadpole; TS, tailshift; D3/4/5, day 3/4/5). Expression of histone genes is mostly driven from short bidirectional promoters, with the exception of several replacement variants (H3.3, H2A.Z, H1.4, H1.3 and CenH3) dispersed as orphan genes. Expression was undetectable for a truncated H3 (H3sh, cluster VIII), likely to be a pseudogene. Light grey arrows indicate non-histone genes.

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