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Figure 7 | BMC Evolutionary Biology

Figure 7

From: Balancing selection is common in the extended MHC region but most alleles with opposite risk profile for autoimmune diseases are neutrally evolving

Figure 7

Haplotype genealogy of the analysed BTNL2 region. Legend is as for figure 3. In (A) positions in bold refer to the following SNPs: 22, rs34423804 (Val189Asp); 23, rs41417449 (Met201Val); 26, rs41441651 (Asp242Asn); 62, rs28362678 (Pro285Leu); 64, rs28362677 (Met286Ile); 65, rs28362676 (Pro299Gln); 69, rs28362675 (Gly360Cys). An enlargement of the major haplotype cluster is also shown (left-upper panel): susceptibility haplotypes for ATD and MS are circled in yellow and cyan, respectively. SNPs numbering is as follows: 27, rs9268480; 28, rs2076530; 100, 3129953.

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BMC Ecology and Evolution

ISSN: 2730-7182

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