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Table 1 Corticosteroid receptor EC50 values

From: Evolution of ligand specificity in vertebrate corticosteroid receptors

 

Aldosterone

DOC

Cortisol

Dexamethasone

Mouse MR

0.20

2.75

1.94

 

Midshipman MR

0.23

0.40

0.20

 

Mouse GR

>1000

--

27.7

2.00

Midshipman GR1

--

--

118.5

5.76

Midshipman GR2

ND

ND

85.9

8.95

  1. Note: EC50 ligand nanomolar concentrations based on logistic regressions. No response is indicated by: --. ND indicates that the EC50 could not be determined based on the curve.
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BMC Ecology and Evolution

ISSN: 2730-7182

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