Figure 4
The number of yeast protein complexes and their random expectation. We consider two kinds of protein complexes. One is those whose members are all of the same age class, and the other is those which are significantly enriched with members from a particular age class. The random expectation is the average of 1000 randomizations which is established by randomizing the corresponding relationships between proteins in the yeast genome and their ages. The empirical P -values are all less than 10-3 . (A) The results are obtained considering all yeast protein complexes. (B) The results are obtained only considering yeast protein complexes without recent paralog pairs (see the Discussion part for the details).