Figure 2

(A) Chromosomal location of the SCD1 and SCD5 genes in Homo sapiens , and their neighbouring genes. Paralogues of gene families with multiple members are shown below each ORF, with distance in Mb to the p telomere of the respective chromosome. Arrows denote gene orientation. Phylogenetic analysis was performed to unveil their duplication pattern (Additional file_1) unless already available. (B) Genomic locus of Branchiostoma floridae SCD-like genes and the neighbouring gene families whose human paralogues localise to expected regions of human SCD paralogy (Hsa10, Hsa4, Hsa5 and Hsa2/8). Gene families with no clear homologues in humans, or gene families that do not localise to the NK-linked paralogon are not labelled (e.g. BfSCDc). The GenBank accession number of each B. floridae SCD scaffold is shown.