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Table 4 Conserved microRNA target sites within the 3'-UTRs of each opsin in O. niloticus and M. zebra

From: Divergence in cis-regulatory sequences surrounding the opsin gene arrays of African cichlid fishes

Opsin miRNA Target Conserved1 Function and expression Ref(s)
SWS1 miR-725 TGACTGAG GA Expressed in fins [55]
SWS2B miR-217 ATGCAGTA GA Alters PTEN exp.; found in eye [75, 78]
SWS2A miR-181a AGAATGTA DR T-cell regulation; found in eye [75, 79]
RH2B miR-23b TATGTGAA TR Ganglion apoptosis; found in eye [77, 116]
RH2Aα/β miR-96 TTGCCAAA OL Sensory organ specific; found in eye [76, 117]
  miR-182a TTGCCAAA OL Sensory organ specific; found in eye [76, 117]
LWS miR-728 TTTAGTAA GA,TN,TR Unknown; found in eye [55]
  miR-722* GCAAAAAA TR Unknown; found in eye [55]
  1. 1 Other fish species in which this target site is also found: GA = stickleback (G. aculeatus), DR = zebrafish (D. rerio), TR = fugu (T. rubripes), TN = pufferfish (T. nigroviridis); OL = medaka (O. latipes)
  2. * This site present in O. niloticus only