Skip to main content

Table 3 Summary of the results of the site-specific analysis: in each case the most significant model was M8

From: Positive selection neighboring functionally essential sites and disease-implicated regions of mammalian reproductive proteins

Gene n Parameter estimates # Positively selected Sites
Adam2 12 p0 = 0.92632 p = 0.37637
q = 0.60688
p1 = 0.07368 ω = 3.94326
45>0.50
15>0.95
5>0.99
Catsper1_Exon1 (primates only) 16 p0 = 0.82736 p = 0.13661
q = 0.03850
p1 = 0.17264 ω = 3.13071
95>0.50
7>0.95
1>0.99
Catsper1_Mammals
(non-primate mammals only)
8 p0 = 0.83315 p = 0.34233
q = 0.51278
p1 = 0.16685 ω = 3.26879
124>0.50
30>0.95
8>0.99
Col1a1 10 p0 = 0.98023 p = 0.04796
q = 0.32286
p1 = 0.01977 ω = 4.09285
66>0.50
21>0.95
8>0.99
Ph20 11 p0 = 0.87658 p = 0.56141
q = 0.83349
p1 = 0.12342 ω = 2.20500
39>0.50
3>0.95
0>0.99
Porimin 10 p0 = 0.85067 p = 0.41864
q = 0.32952
p1 = 0.14933 ω = 12.21841
30>0.50
13>0.95
5>0.99
Prkar2a 17 p0 = 0.95102 p = 0.16339
q = 0.98823
p1 = 0.04898 ω = 2.60992
19>0.50
4>0.95
0>0.99
Semg2 12 p0 = 0.97236 p = 0.01163
q = 0.00500
p1 = 0.02764 ω = 12.26405
41>0.50
5>0.95
2>0.99
Sp56 14 p0 = 0.98807 p = 0.16114
q = 1.12262
p1 = 0.01193 ω = 3.81710
8>0.50
2>0.95
2>0.99
Zp2 18 p0 = 0.87339 p = 0.63945
q = 0.75356
p1 = 0.12661 ω = 2.04655
52>0.50
9>0.95
6>0.99
Zp3 13 p0 = 0.91489 p = 0.30029
q = 0.77328
p1 = 0.08511 ω = 1.92305
48>0.50
0>0.95
0>0.99
  1. Following LRT analysis M8 was chosen in each case as the most significant model. n refers to the number of taxa in each dataset. The proportion of sites (p), evolving under each corresponding selective pressures (ω) are shown. For example, p0 refers to the proportion of the protein evolving under the selective pressure value given by ω0. The parameters p and q describe the beta distribution. The final column gives the number of sites with posterior probability (PP) of 0.50, 0.95 and 0.99 that belong in the positively selected category or sites. The number before the ">" refers to the number of sites with a specific PP value.
\