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Figure 3 | BMC Evolutionary Biology

Figure 3

From: MHC allele frequency distributions under parasite-driven selection: A simulation model

Figure 3

Exemplary trajectories of P H statistic (top panel) and allele frequencies (middle and bottom panels) for host populations attacked by 25 pathogen species and for heterozygote advantage only. The blue line in the top panel represents trajectory of PH statistic while the red dashed line demarcates threshold of PH = 0.025 below which allele frequencies are considered to significantly differ from neutrality. Allele trajectories, represented in the middle and bottom panels, were split into two groups: low frequency (< 0.15) (bottom panel) and high frequency (> 0.15) (middle panel) for clarity of presentation. Thick colour lines represent trajectories of alleles emerging or lost from a host population during the sampled period, all other ones are in grey.

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