Figure 2From: Evolution and functional divergence of the anoctamin family of membrane proteinsAverage hydropathy plot of 166 homologues of vertebrate bestrophins. Hydropathy plot was generated from 166 vertebrate sequences as given in Additional file 1 using TMAP server which predicts transmembrane segments from an aligned set of proteins. Amino acid numbering corresponds to the numbers from the multiple sequence alignment. Black boxes depict predicted TMD's. RL = re-entry loopBack to article page