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Table 5 The time to the most recent ancestor (TMRCA) of different segments of enterovirus 71 derived from this study.

From: Inferring nonneutral evolution from contrasting patterns of polymorphisms and divergences in different protein coding regions of enterovirus 71 circulating in Taiwan during 1998-2003

Lineage

Beginning of the outbreak

Genomic region

TMRCA

95% HPD

Lineage 1

2001.2

VP1

2000.8

(2000.8)

2000.5~2001.1

(2000.3~2001.1)

  

2A

2000.8

2000.3~2001.1

  

3C

2000.8

2000.4~2001.0

  

5'UTR

2000.4

1999.9~2000.9

Lineage 2 and 3

1999.8

VP1

1998.6

(1997.8)

1997.9~1999.2

(1997.1~1998.4)

  

2A

1998.9

1998.3~1999.4

  

3C

1998.8

1998.2~1999.3

  

5'UTR

1998.8

1998.1~1999.4

Lineage 7

1998.3

VP1

1997.2

(1997.3)

1995.6~1998.1

(1996.7~1997.8)

  

2A

1998.1

1997.4~1998.2

  

3C

1997.3

1984.4~1998.4

  

5'UTR

1998.0

1997.7~1998.2

  1. Numbers in parentheses are TMRCA estimated with seqeunces from surrounding areas (see text for details)
  2. HPD, highest posterior density.