Table 3 Amino acid physicochemical properties under positive destabilizing selection in fru C3 exon.
From: Evidence for positive selection in the gene fruitless in Anastrephafruit flies
Physicochemical property | Goodness-of-fit (neutral expectation) | radical change category (6, 7 e 8) | z-score |
|---|---|---|---|
Alpha-helical tendencies (P α ) | 36.498*** | 8 | 1.975* |
Average number of surrounding residues (N s ) | 76.820*** | - | - |
Beta-structure tendencies (P β ) | 67.631*** | - | - |
Bulkiness (B l ) | 40.169*** | - | - |
Buriedness (B r ) | 47.688*** | - | - |
Chromatographic index (R f ) | 65.981*** | - | - |
Coil tendencies (P c ) | 82.908*** | - | - |
Composition (C) | 52.020*** | - | - |
Compressibility (K0) | 36.874*** | - | - |
Equilibrium constant (ionization of COOH) (pK') | 33.814*** | - | - |
Helical contact area (C a ) | 41.651*** | - | - |
Hydropathy (H) | 92.128*** | 6 | 4.972*** |
Isoelectric point (pH i ) | 56.298*** | - | - |
Long-range non-bonded energy (E l ) | 38.021*** | - | - |
Mean r.m.s. fluctuation displacement (F) | 57.826*** | - | - |
Molecular volume (M v ) | 48.275*** | - | - |
Molecular weight (M w ) | 53.230*** | 6 | 3.928*** |
Normalized consensus hydrophobicity (H nc ) | 29.042*** | - | - |
Partial specific volume (V0) | 22.173** | - | - |
Polar requirement (P r ) | 77.854*** | - | - |
Polarity (P) | 117.046*** | - | - |
Power to be at the C-terminal of alpha-helix (α c ) | 57.177*** | - | - |
Power to be at the middle of alpha-helix (α m ) | 40.309*** | - | - |
Power to be at the N-terminal of alpha-helix (α n ) | 35.782*** | - | - |
Refractive index (μ) | 17.263* | - | - |
Short and medium range non-bonded energy (E sm ) | 73.460*** | - | - |
Solvent accessible reduction ratio (R a ) | 16.175* | - | - |
Surrounding hydrophobicity (H p ) | 90.284*** | - | - |
Thermodynamic transfer hydrophobicity (H t ) | 90.401*** | - | - |
Total non-bonded energy (E t ) | 32.042*** | - | - |
Turn tendencies (P t ) | 45.706*** | - | - |