Figure 3

Comparison of ARGFX , OTX1 , OTX2 and CRX gene structures. Human TPRX1, DPRX, HESX1 and GSC gene structures were used as references. Exons are represented by boxes and introns by lines, with the length in nucleotides written above. The 5' and 3' untranslated regions are shown in white and the protein coding regions in black except for homeodomains which are shown in red. Human gene structures follow the NCBI gene annotation; tree shrew and megabat ARGFX intron positions were deduced by reference to retroposed pseudogenes.