Figure 5

Duplication dynamics histograms. Left: Histogram to detect directional bias for the MSY1 dataset. The distribution of E _n of the randomized data is centered around zero. The peak at point 1 on the x-axis is for E _n of the original dataset, and it is clearly far from that of data with expected equal rates of left-to-right and right-to-left duplications. Right: Histogram to detect directional bias for the MS205 dataset. The peak on the left on the x-axis is for E _n of the original dataset.