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Table 1 Amino acid combinations at the protein protein interaction surface.

From: WD-repeat instability and diversification of the Podospora anserina hnwd non-self recognition gene family

A/

    

B/

    
 

Position

 

Position

 

7

9

25

27

 

7

9

25

27

e1-1(snWD)

S

L

N

K

r10-5(dWD)

S

S

G

D

e1-9(snWD)

W

H

D

H

r11-2(dWD)

S

Y

D

D

e3-2(snWD)

T

W

D

K

r11-3(dWD)

S

S

G

D

e5-2(gWD)

S

W

S

N

r11-5(dWD)

S

S

G

D

e5-4(gWD)

S

W

D

H

het-R-1

S

Y

G

R

e6-3(gWD)

R

Q

D

K

het-R-2

S

Y

V

D

e7-7(gWD)

W

Q

D

K

het-R-3

S

Y

G

D

e9-5(dWD

S

W

I

D

het-R-4

S

S

V

R

het-E-1

S

L

D

K

het-R-5

S

S

V

D

het-E-2

S

W

D

K

het-R-6

S

S

G

R

het-E-3

R

Q

D

H

het-R-7

W

Y

G

D

het-E-4

S

L

G

K

het-R-8

S

S

D

D

het-E-5

S

W

G

K

het-R-9

L

Y

G

D

het-E-6

S

W

D

K

het-R-10

S

H

V

D

het-E-7

W

Q

D

H

het-R-11

S

S

V

C

het-E-8

S

W

I

G

     

het-E-9

W

H

I

G

     

het-E-10

W

Q

S

K

     

het-E-11

W

Q

S

N

     
  1. The four amino acids at positions under selection in newly generated alleles (underlined) are amino acids found in the parental sequences (white boxes) for A/the het-E gene, and B/the het-R gene. Bolded pairs of amino acids were generated in the mutants. Repeats are named after their positions in the mutated alleles, the class of the corresponding mutant is indicated in brackets.