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Table 3 Pairs of genes and their paralogs

From: Divergence of imprinted genes during mammalian evolution

group

genes

with paralog

median number of paralogs

most recent paralog on X

has a paralog on X

average protein identity ± std.dev. (%)a

human imprinted

56

34*

2

3

6

47.12 ± 15.24**

human autosomes

19,950

9619

2

288

1035

56.85 ± 22.73

mouse imprinted

54

33*

2*

2

4

44.94 ± 18.02***

mouse autosomes

21,871

10919

3

309

1029

60.68 ± 24.07

  1. aIn cases where more than one paralog was available, protein identities were analyzed only for the gene and its evolutionary most recent paralog. * p < 0.1, ** p < 0.05, *** p < 0.001 (χ2 or Wilcoxon test for comparison of the respective imprinted group to autosomal data)