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Table 3 Virulence of analysed Trichomonas vaginalis strains assessed on the basis of clinical findings, histopathological examination of ectocervical biopsies and results of mouse assays after intraperitoneal and subcutaneous inoculation.

From: Concordance between genetic relatedness and phenotypic similarities of Trichomonas vaginalis strains

  Intraperitoneal mouse test Subcutaneous mouse test Patients(d)
Strain Mortality % (a) Virulence index (b) N Abscess volume (mm3) (c) N Symptoms Histopathology
TV 85–08 50 7.7 20 132 38 2 2
TV 73–87 43 10.4 30 66 31 2 2
TV 71–96 24 6.0 37 121 38 2 3
TV 79–49 73 10.7 30 176 65 1 1
TV 14–85 86 10.8 30 127 29 4 3
TV 67–77 47 8.7 30 63 40 2 2
TV 10–02 0 3.7 20 79 37 1 1
TV 7–37 90 13.4 30 230 41 4 4
FF28 75 7.6 12 117 28 0 nd
JH-31A nd nd nd 78.6 49 0 0
TV 17–48 83 11.1 30 183 58 4 4
  1. (a) Percent of inoculated mice that died within three weeks after inoculation. (b) Virulence index of Cavier et al.[23] ranges from 0 (avirulent) to 16 (maximum virulence). (c) Mean volumes of subcutaneous abscesses developed six days after inoculation. (d) Clinical and pathological changes found at gynaecological and histopathological examination rated according to increasing severity from 1 to 4 as indicated in reference [2].